Description

Product Description

SPACE Peptide (CAS 1621717-95-0) is a next-generation skin-penetrating peptide (SPP) engineered to improve the transdermal transport and absorption of high-molecular-weight compounds in cosmetic and dermatological research. This peptide represents a significant advancement in the field of skin delivery systems, enabling enhanced bioavailability of active agents such as hyaluronic acid, peptides, antioxidants, and growth factors that typically face absorption barriers when applied topically.

As a biocompatible and non-toxic peptide, SPACE Peptide exhibits strong affinity for lipid membranes, allowing it to transiently modulate skin barrier properties and facilitate the diffusion of otherwise poorly permeable compounds. It functions by temporarily reorganizing the stratum corneum’s lipid structure, reducing intercellular resistance without compromising long-term skin integrity.

In cosmetic peptide research, SPACE Peptide is recognized for its capacity to enhance formulation efficacy, leading to increased hydration, elasticity, and visible improvement in the delivery of anti-aging, brightening, and repair-related actives. It can be incorporated into diverse formulations — including serums, creams, and hydrogels — as a carrier enhancer for functional ingredients.

Furthermore, SPACE Peptide plays an essential role in the study of cutaneous pharmacokinetics, offering a valuable model for understanding how molecular size, charge, and lipophilicity influence dermal penetration. The peptide’s compatibility with both hydrophilic and lipophilic compounds makes it a versatile component in experimental transdermal systems designed for cosmetic and biomedical applications.

In the context of cosmetic science, SPACE Peptide supports innovative formulation strategies aimed at improving delivery precision and bioactive stability. By facilitating macromolecular transport, it allows researchers to achieve deeper skin targeting of compounds such as collagen stimulators, hyaluronic acid polymers, and antioxidative peptides, fostering more efficient cellular interaction and functional outcomes.

The peptide’s role as a skin permeability enhancer does not rely on chemical irritation or mechanical disruption, making it suitable for the exploration of gentle, non-invasive skincare delivery systems. It also aids in the stabilization and preservation of sensitive bioactives within emulsions and aqueous matrices, further increasing the longevity and performance of topical applications.

Through ongoing research, SPACE Peptide continues to redefine skin penetration enhancement technology, contributing to a new generation of high-performance cosmetic formulations that combine efficacy, safety, and biomimetic design.

Product Specifications

Mechanism of Action

SPACE Peptide functions as a transdermal carrier enhancer, operating at the interface of biophysical modulation and peptide-membrane interaction. Its amphipathic sequence allows the molecule to insert reversibly into lipid bilayers, creating temporary microchannels that increase the permeability of the stratum corneum — the primary barrier to skin absorption.

At the molecular level, the peptide’s hydrophobic residues interact with the lipid tails of the stratum corneum, while hydrophilic regions maintain contact with aqueous environments. This dual affinity allows SPACE Peptide to form transient structures that reduce diffusion resistance, enhancing molecular transport without causing structural damage or inflammation.

In cosmetic research, SPACE Peptide has been demonstrated to amplify the dermal delivery of actives such as hyaluronic acid by increasing intracellular and intercellular permeability. This results in enhanced moisture retention, improved viscoelasticity, and optimized cellular uptake of bioactive compounds related to anti-aging, pigmentation control, and antioxidant defense.

Moreover, SPACE Peptide contributes to enhanced bioavailability of peptide-based actives, supporting synergistic effects with ingredients like collagen-boosting hexapeptides, copper tripeptides, or glutathione derivatives. It acts as a functional delivery platform, capable of improving both penetration depth and duration of bioactivity in topical applications.

In experimental dermatology, SPACE Peptide is studied as part of smart peptide delivery systems, integrating with nanocarriers, liposomes, and micellar systems to achieve multi-phase absorption control. Its reversible and non-denaturing activity ensures sustained peptide integrity and minimizes irritation, aligning with modern formulation goals of biocompatibility and long-term skin health.

Side Effects

In cosmetic and dermatological research contexts, SPACE Peptide is generally regarded as non-toxic, biocompatible, and non-irritating. Extensive in vitro and ex vivo testing indicates minimal cytotoxicity and no evidence of inflammatory response or cellular stress when used at research concentrations.

Possible observations in over-concentrated formulations may include transient redness or mild dryness due to temporary changes in barrier permeability. Such effects are reversible and typically diminish once formulations are adjusted to optimal peptide concentrations.

Since SPACE Peptide is designed for research purposes, it is not approved for clinical or topical consumer application. Researchers should evaluate dose–response relationships and conduct standard skin patch compatibility assays before applying it in complex formulation systems.

Keywords

SPACE Peptide, CAS 1621717-95-0, skin-penetrating peptide, transdermal delivery enhancer, cosmetic peptide, hyaluronic acid delivery, peptide carrier, biomimetic penetration enhancer, peptide skin absorption, dermal delivery research.

Shipping Guarantee

All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.