Description
Product Description
Myristoyl tetrapeptide-12 dihydrochloride is a synthetic peptide compound designed for advanced cosmetic research focusing on hair and scalp health. Structurally, it combines a short peptide sequence containing lysine and alanine residues with a myristoyl lipid chain, which enhances lipophilicity and skin penetration. This amphiphilic structure allows the peptide to interact effectively with the hair follicle and epidermal layers, facilitating bioavailability and stability in topical formulations.
In cosmetic research, Myristoyl tetrapeptide-12 dihydrochloride is recognized for its ability to support the natural growth cycle of hair, fortify follicular structures, and maintain the extracellular matrix surrounding hair roots. The compound’s dual peptide-lipid composition enables better adhesion to keratin-rich tissues, allowing it to act as a carrier for strengthening signals that enhance tensile resistance and prevent breakage.
The peptide also demonstrates potential antioxidant and anti-inflammatory properties, which may reduce oxidative stress around follicles—a key factor contributing to premature hair thinning and scalp irritation. By modulating cellular activity within the dermal papilla, Myristoyl tetrapeptide-12 dihydrochloride contributes to improved microcirculation, nutrient delivery, and collagen synthesis, supporting healthy scalp environments in research settings.
Owing to its versatility, Myristoyl tetrapeptide-12 dihydrochloride has been incorporated into various cosmetic peptide formulations aimed at hair rejuvenation, scalp care, and anti-aging applications. Its compatibility with hyaluronic acid, plant-derived extracts, and lipid-based emulsions makes it suitable for exploration in multifunctional cosmetic systems designed for long-term strengthening and protection.

Product Specifications
| Property | Description |
|---|---|
| Product Name | Myristoyl tetrapeptide-12 dihydrochloride |
| CAS Number | — |
| Purity | ≥99% |
| Synonyms | Myristoyl Tetrapeptide-12·2HCl |
| Molecular Formula | — |
| Molecular Weight | — |
| Appearance | White to off-white powder |
| Solubility | Soluble in water and aqueous buffer |
| Category | Cosmetic Peptide / Hair Care Peptide |
| Storage | Store at -20°C, protected from light and moisture |
| Shelf Life | 3 years under proper storage conditions |
Mechanism of Action
Myristoyl tetrapeptide-12 dihydrochloride exerts its biological activity primarily through biomimetic stimulation of extracellular matrix (ECM) components within the dermal layer and hair follicle root sheath. The peptide’s myristoyl chain enables efficient penetration through the stratum corneum, allowing it to reach deeper follicular regions where it can interact with fibroblasts and keratinocytes.
By promoting the expression of ECM proteins such as collagen, laminin, and fibronectin, this peptide aids in maintaining structural cohesion around the follicle bulb. The increased structural support facilitates a healthier growth environment, contributing to improved anchorage of hair fibers and enhanced scalp elasticity in laboratory research models.
Additionally, Myristoyl tetrapeptide-12 dihydrochloride may activate signaling pathways associated with cellular renewal, including the stimulation of integrin receptors and the regulation of growth factors responsible for keratinocyte proliferation. It also contributes to reducing inflammatory cytokine release, thus minimizing scalp sensitivity and oxidative stress.
The peptide’s functional mechanism further extends to moisture retention and barrier repair. By improving lipid balance and increasing hydration at the scalp surface, it supports research into formulations targeting dry, brittle, or aging hair. These combined effects make it a potent bioactive molecule in the cosmetic peptide category for anti-aging hair care studies.

Side Effects
Based on available research and laboratory testing, Myristoyl tetrapeptide-12 dihydrochloride demonstrates good tolerability and minimal adverse reactions in vitro. Its biocompatibility and mild nature make it suitable for inclusion in topical studies involving peptide-based cosmetic formulations.
However, researchers should note that all testing must be conducted under controlled laboratory conditions. Any observed irritation or sensitivity should be monitored carefully, as outcomes may vary depending on concentration, formulation matrix, and experimental protocol. As with all cosmetic peptide research compounds, it is essential to ensure appropriate handling and dilution to prevent potential overexposure.
Keywords
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Shipping Guarantee
All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance
We ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.
Payment Support
We provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.
Disclaimer
All products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.






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