Description
Product Description
Oligopeptide-10 (CAS 466691-40-7) is a bioactive peptide designed for cosmetic research applications that target skin health and microbial protection. As a naturally inspired peptide, Oligopeptide-10 exhibits anti-microbial activity against a range of skin-relevant microorganisms, including Staphylococcus aureus and Propionibacterium acnes, which are implicated in acne and other inflammatory skin conditions.
The peptide acts as a modulator of innate skin defense mechanisms, enhancing the skin’s natural protective barriers while minimizing potential irritation. In cosmetic research, it is investigated for its ability to:
Promote healthy skin microbiota balance
Support epidermal barrier integrity
Reduce oxidative stress and inflammatory responses
Protect dermal fibroblasts from microbial-induced damage
Oligopeptide-10 can be incorporated into in vitro studies for testing anti-microbial efficacy in cosmetic formulations, including serums, creams, and emulsions. Its small size and water solubility enable easy integration into delivery systems, facilitating enhanced skin penetration and bioavailability.
Additionally, Oligopeptide-10 exhibits synergistic effects with other cosmetic peptides, such as Copper Tripeptide-3, Acetyl Hexapeptide-8, and Palmitoyl Tripeptides, to further enhance skin repair, hydration, and elasticity.
In advanced research, this peptide is also used to explore:
Anti-aging effects through fibroblast stimulation and collagen upregulation
Modulation of keratinocyte differentiation and proliferation
Protective mechanisms against UV-induced oxidative stress
This makes Oligopeptide-10 a valuable tool for cosmetic peptide research aimed at developing skin-protective, anti-aging, and anti-microbial products.

Product Specifications
| Property | Description |
|---|---|
| Product Name | Oligopeptide-10 |
| CAS Number | 466691-40-7 |
| Synonyms | Anti-Microbial Peptide Oligopeptide-10 |
| Molecular Formula | C₄₄H₇₀N₁₂O₁₂ |
| Molecular Weight | 958.08 g/mol |
| Purity | ≥99% |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in water |
| Storage | -20°C, protected from light and moisture |
| Formulation | Lyophilized peptide (research-grade) |
| Applications | Anti-microbial, skin barrier, cosmetic peptide research |
| Category | Cosmetic peptide |
| Origin | Synthetic |
| Intended Use | For laboratory research use only |
Mechanism of Action
Oligopeptide-10 functions primarily as an anti-microbial and skin-protective agent. It exerts its effect by:
Disrupting microbial membranes – The peptide interacts with microbial cell membranes, causing destabilization and increased permeability, leading to inhibition of bacterial growth.
Enhancing skin barrier peptides – It upregulates endogenous antimicrobial peptides in keratinocytes, supporting innate skin defense.
Reducing inflammation – By modulating pro-inflammatory cytokines, it minimizes the skin’s inflammatory response to microbial insult.
Promoting collagen and ECM repair – Secondary effects include stimulation of dermal fibroblasts, which enhances collagen deposition and tissue repair, contributing to overall anti-aging benefits.
These combined mechanisms make Oligopeptide-10 highly valuable in cosmetic research for developing skin-protective and anti-aging peptide formulations.

Side Effects
Oligopeptide-10 is generally considered low-risk and non-toxic in research-grade use. Observed effects in vitro include:
Mild skin cell irritation at very high concentrations (>10 μM)
No reported systemic toxicity
No mutagenic or allergenic effects
As this product is intended for research purposes only, it must not be administered to humans or animals. Researchers should follow standard laboratory biosafety and chemical handling guidelines.
Keywords
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Shipping Guarantee
All shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.
Trade Assurance
We ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.
Payment Support
We provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.
Disclaimer
All products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.






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