Description
Product Description
Angio-S is a synthetic bioactive peptide designed to support vascular and dermal tissue health. As the skin ages, vascular integrity and nutrient delivery decline, leading to dullness, reduced elasticity, and compromised regenerative capacity. Angio-S has been studied for its ability to maintain healthy microcirculation, support endothelial function, and enhance cellular metabolism in the dermis, making it a valuable ingredient in the field of cosmetic peptide research.
The research on Angio-S has shown its promising potential in promoting angiogenesis at the microvascular level, stimulating the formation of new capillaries, and improving oxygen delivery to the skin. These processes play a critical role in maintaining youthful skin texture and tone. The peptide also contributes to reducing oxidative stress by modulating endothelial nitric oxide synthase (eNOS) activity, which in turn promotes better vasodilation and skin vitality.
In vitro and in vivo studies suggest that Angio-S enhances fibroblast activity, leading to increased synthesis of extracellular matrix proteins such as collagen and elastin. This biological activity contributes to improved dermal density and firmness, addressing signs of aging caused by environmental exposure and intrinsic skin thinning. Researchers have also explored its role in improving wound healing processes and post-procedural skin recovery.
Another focus of cosmetic research is the use of Angio-S in formulations targeting periorbital and facial microcirculation, as impaired blood flow is linked to dark circles and uneven complexion. By strengthening the vascular walls and increasing capillary resistance, Angio-S may help mitigate these issues through enhanced nutrient transport and oxygen supply to the skin tissues.
Due to its multi-targeted bioactivity, Angio-S is commonly evaluated in anti-aging formulations, regenerative serums, and post-procedure recovery systems. It provides a scientific foundation for cosmetic researchers aiming to develop products that support both dermal repair and vascular function.
Researchers also value Angio-S for its stability, compatibility with various peptide-based formulations, and excellent bioavailability in topical systems. It can be incorporated into emulsions, gels, or liposomal carriers to improve penetration and activity within dermal layers. The peptide’s amphiphilic structure enhances solubility and peptide uptake in skin models, enabling consistent performance in research applications.
As a cosmetic research peptide, Angio-S demonstrates potential synergistic effects when combined with antioxidants, growth factors, or other biomimetic peptides. In particular, combining Angio-S with peptides that stimulate collagen synthesis or inhibit melanin overproduction may lead to comprehensive skin rejuvenation strategies. This makes it an ideal peptide for ongoing research into cosmetic formulations aimed at restoring youthful, radiant skin appearance.
Overall, Angio-S stands out as a promising compound in cosmetic peptide science. It bridges the research between vascular biology and dermal restoration, offering a molecular approach to studying how enhanced blood circulation and tissue regeneration can contribute to visible improvements in skin tone, texture, and elasticity.
Product Specifications
| Item | Description |
|---|---|
| Product Name | Angio-S |
| CAS Number | 1114970-34-1 |
| Purity | ≥99% |
| Synonyms | Peptide Angio S; Vascular Repair Peptide |
| Molecular Formula | N/A |
| Molecular Weight | N/A |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in water and PBS buffer |
| Storage | Store at -20°C, protected from light and moisture |
| Category | Cosmetic Peptide |
| Applications | Anti-aging, skin regeneration, vascular function research |
| Research Area | Skin repair, microcirculation, dermal regeneration |
| Supplier Type | Factory peptide supplier |
| Language | English |
| Intended Use | For laboratory research use only |
Mechanism of Action
Angio-S acts primarily through modulation of vascular endothelial cell signaling pathways. The peptide enhances endothelial nitric oxide synthase (eNOS) activity, leading to improved vasodilation and better oxygen and nutrient transport across dermal layers. By supporting angiogenic signaling, Angio-S encourages the formation of new capillaries, increasing microvascular density and skin vitality.
The mechanism also involves upregulation of growth factors associated with skin repair, such as VEGF (Vascular Endothelial Growth Factor) and FGF (Fibroblast Growth Factor). This dual stimulation accelerates fibroblast proliferation and extracellular matrix renewal. Enhanced fibroblast activity increases collagen and elastin synthesis, contributing to firmer, more elastic skin.
In addition to promoting angiogenesis, Angio-S demonstrates antioxidant properties. By reducing reactive oxygen species (ROS) and oxidative lipid peroxidation, it protects cellular structures from environmental damage. This is especially valuable in combating the signs of aging induced by UV exposure and pollution.
The peptide’s impact on the vascular endothelium supports a more balanced skin microenvironment. Improved blood flow facilitates nutrient delivery and metabolic waste removal, creating optimal conditions for dermal cell function. Furthermore, Angio-S enhances the barrier function of the skin by reinforcing dermal-epidermal junction proteins, which improves resilience and hydration retention.
Research also suggests that Angio-S plays a role in reducing inflammation. It downregulates pro-inflammatory cytokines and inhibits endothelial activation, resulting in a calmer, more even skin tone. By promoting anti-inflammatory pathways and restoring microcirculatory efficiency, Angio-S supports both short-term rejuvenation and long-term skin health.

Side Effects
In cosmetic research, Angio-S has shown an excellent safety profile. No cytotoxic or irritative reactions have been reported at concentrations typically used in research formulations. However, as with all peptides, researchers are advised to conduct concentration optimization studies and stability testing under different pH and formulation conditions.
Due to its bioactive nature, improper handling or formulation errors could potentially alter its efficacy. Thus, laboratory researchers should handle the peptide with standard biosafety and chemical safety precautions. The peptide is not intended for human or animal administration.
Keywords
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Shipping Guarantee
All Angio-S shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.
Trade Assurance
We ensure Angio-S product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.
Payment Support
We provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.
Disclaimer
All Angio-S products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.



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