Description

Product Description

Hexapeptide-42 is a synthetic bioactive peptide consisting of six amino acids designed to support skin regeneration and structural repair. It plays a critical role in promoting extracellular matrix (ECM) renewal, stimulating collagen synthesis, and restoring the skin’s elasticity and firmness — key targets in modern cosmetic research. As a functional peptide, Hexapeptide-42 helps minimize the visible signs of aging, including fine lines, wrinkles, and loss of skin tone.

In the process of skin aging, fibroblast function diminishes and the rate of collagen and elastin production declines. This leads to dermal thinning, decreased mechanical strength, and reduced barrier performance. Hexapeptide-42 counteracts these biological changes by promoting fibroblast proliferation, enhancing ECM integrity, and supporting balanced cell signaling pathways involved in dermal reconstruction.

Recent studies indicate that Hexapeptide-42 can upregulate type I and III collagen expression and increase elastin fiber density. It also strengthens intercellular cohesion, which results in improved skin texture and resilience. Its small molecular size enables deep dermal penetration, allowing it to act effectively in the skin’s basal layer where regenerative processes occur.

As an advanced anti-aging research peptide, Hexapeptide-42 offers a safe and efficient pathway to study biomimetic mechanisms of dermal rejuvenation. It has been incorporated into cosmetic formulations designed to support tissue regeneration, barrier restoration, and wrinkle reduction. Researchers have observed that Hexapeptide-42 enhances the synthesis of structural proteins and modulates gene expression associated with skin homeostasis.

In cosmetic research, Hexapeptide-42 is valued for its stability, biocompatibility, and ability to deliver visible results without irritation. It is often combined with other bioactive peptides—such as Palmitoyl Pentapeptide-4 or Acetyl Hexapeptide-8—to achieve synergistic anti-aging effects. Its consistent performance in laboratory studies makes it a reliable component for advanced peptide-based skincare innovation.

Product Specifications

Mechanism of Action

Hexapeptide-42 operates by activating multiple biological pathways responsible for maintaining dermal structure and function:

1. Stimulation of Collagen and Elastin Synthesis
   It enhances fibroblast activity, increasing the production of type I and III collagen and elastin, which strengthens skin structure.

2. Regulation of Cell Communication
   Hexapeptide-42 supports balanced communication between fibroblasts and keratinocytes, ensuring coordinated ECM reconstruction.

3. Barrier Repair and Protection
   The peptide helps rebuild the skin barrier by improving the integrity of corneocyte connections and lipid balance.

4. Antioxidant and Detoxification Support
   It indirectly reduces oxidative stress by maintaining enzymatic antioxidant defenses in skin cells.

5. Anti-Inflammatory Action
   By normalizing cytokine activity, Hexapeptide-42 helps calm irritation and reduces microinflammation that accelerates aging.

6. Tissue Remodeling and Regeneration
   Studies suggest that Hexapeptide-42 upregulates genes associated with wound healing and ECM turnover, contributing to smoother and more resilient skin.

Overall, Hexapeptide-42 demonstrates a biomimetic mode of action, closely replicating the body’s natural repair and anti-aging mechanisms.

Side Effects

Hexapeptide-42 is considered safe and non-toxic for laboratory use. It has demonstrated a favorable safety profile in cosmetic research studies.

Potential considerations include:

• Mild transient irritation if applied at high concentrations in test models.

• Degradation under prolonged exposure to light or heat.

• All peptides should be handled under controlled storage conditions (−20°C) to maintain purity and activity.

No mutagenic or cytotoxic effects have been observed in standard testing. Proper formulation practices ensure maximum stability and performance.

Keywords

Hexapeptide-42, bioactive peptide, cosmetic peptide, anti-aging peptide, collagen peptide, skin regeneration peptide, wrinkle reduction peptide, OEM peptide production, peptide wholesale China, factory peptide supplier, China peptide manufacturer, high-purity cosmetic peptides.

Shipping Guarantee

All Hexapeptide-42 shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We Hexapeptide-42 provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All Hexapeptide-42 products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.