Description

Product Description

Oligopeptide-41 is a multifunctional bioactive peptide that has attracted increasing attention in cosmetic and dermatological research due to its ability to promote hair growth and revitalize hair follicles. This peptide works by enhancing cellular communication and stimulating the activity of key growth factors involved in follicle regeneration, such as VEGF (vascular endothelial growth factor) and IGF-1 (insulin-like growth factor-1).

Hair loss and scalp thinning are often linked to oxidative stress, microinflammation, and reduced blood circulation around the follicles. Oligopeptide-41 helps counteract these effects by stimulating dermal papilla cells, improving oxygen and nutrient supply, and enhancing the metabolic activity of follicular keratinocytes. Through these biological processes, it contributes to a healthier scalp microenvironment and the visible improvement of hair density and texture.

In cosmetic peptide research, Oligopeptide-41 has demonstrated the ability to extend the anagen (growth) phase of the hair cycle while delaying the transition to the catagen (regression) phase. This mechanism effectively increases hair strand retention and boosts follicular vitality. Researchers have noted its synergistic effects when combined with other active peptides such as Acetyl Tetrapeptide-3 and Copper Tripeptide-1, making it a versatile ingredient in multi-functional formulations targeting both scalp aging and follicular repair.

Oligopeptide-41 also contributes to anti-aging studies beyond hair growth. By activating fibroblast proliferation and promoting extracellular matrix production, it enhances skin elasticity and strengthens dermal structure. This dual functionality makes it a valuable peptide for exploring new strategies in skin–hair interface rejuvenation research.

The peptide is typically provided as a lyophilized powder, soluble in aqueous and mild ethanol solutions, and highly stable when stored at low temperature. It can be incorporated into formulations such as hair serums, scalp treatments, or research emulsions intended for laboratory testing.

Product Specifications

Mechanism of Action

The mechanism of Oligopeptide-41 revolves around its ability to stimulate dermal papilla cells and activate growth factor pathways that support hair regeneration. By mimicking natural signaling peptides, Oligopeptide-41 enhances cellular communication between the dermis and epidermis, promoting optimal conditions for hair follicle activity.

1. Activation of Growth Factors

Oligopeptide-41 upregulates the expression of VEGF and IGF-1, two critical mediators of hair follicle vascularization and cell proliferation. VEGF increases microcirculation around the follicle, ensuring better oxygenation, while IGF-1 supports keratinocyte and fibroblast vitality.

2. Regulation of Hair Cycle Phases

By extending the anagen phase and delaying the catagen phase, Oligopeptide-41 sustains continuous follicle productivity. This results in stronger, denser, and more resilient hair growth, aligning with studies on peptides that regulate dermal papilla function.

3. Anti-Inflammatory and Antioxidant Support

Chronic inflammation and oxidative stress are key factors in hair loss and scalp aging. Oligopeptide-41 exhibits antioxidant activity that mitigates ROS (reactive oxygen species) accumulation and reduces microinflammatory cytokines such as IL-6 and TNF-α, preserving follicle health.

4. Collagen and ECM Support

The peptide supports the extracellular matrix (ECM) by enhancing collagen synthesis and elastin fiber organization. A stable ECM provides the structural foundation necessary for robust follicle anchoring and long-term scalp elasticity.

5. Synergy with Other Cosmetic Peptides

When used alongside Acetyl Tetrapeptide-3, Palmitoyl Tripeptide-5, or Biotinoyl Tripeptide-1, Oligopeptide-41 amplifies results in terms of follicular density and scalp resilience, offering an innovative multi-pathway approach to peptide-based hair rejuvenation.

Overall, Oligopeptide-41 functions as a multi-mechanistic hair growth enhancer with strong potential in research related to trichology, cellular communication, and peptide-mediated tissue repair.

Side Effects

In laboratory settings, Oligopeptide-41 has shown excellent stability and safety profiles. It is non-toxic, non-sensitizing, and compatible with most cosmetic formulation bases. Studies have not reported significant adverse effects on keratinocytes or dermal fibroblasts even at high concentrations.

However, as with all peptides intended for research use only, users must handle the material following proper biosafety and chemical handling protocols. Direct topical application in untested formulations should be avoided until full toxicological evaluations are performed.

The peptide’s degradation products are non-hazardous under neutral pH, and it remains stable for up to 24 months under recommended storage conditions.

Keywords

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Shipping Guarantee

All Oligopeptide-41 shipments are handled using validated cold-chain logistics to preserve peptide integrity. Each package is sealed in moisture-proof containers with secondary protective wrapping and continuous temperature monitoring. Products are shipped via express international couriers with full tracking and insurance coverage.

Trade Assurance

We Oligopeptide-41 ensure product authenticity, verified ≥99% purity, and compliance with analytical standards (HPLC, MS, and NMR). Each batch is supplied with a Certificate of Analysis (CoA). Our trade assurance policy guarantees replacement or refund for any deviation from listed specifications.

Payment Support

We Oligopeptide-41 provide flexible and secure global payment options to support international research transactions. Accepted payment methods include PayPal, major credit cards (Visa, MasterCard, American Express), telegraphic transfer (T/T), and cryptocurrencies (USDT, Bitcoin, Ethereum). All transactions are protected by industry-standard encryption and verified payment gateways to ensure confidentiality and fund security.

Disclaimer

All Oligopeptide-41 products listed are intended for laboratory research use only and not for human or veterinary use. They are not drugs, medical devices, or diagnostics and should not be administered to humans or animals. Researchers must handle all materials in accordance with institutional biosafety and chemical safety guidelines. The information provided is for scientific reference only and does not imply therapeutic efficacy, safety, or regulatory approval.