Description
Dienogest Tablets Product Specifications
| Attribute | Details |
|---|---|
| Product Name | Dienogest Tablets (Changyining) |
| Generic Name | Dienogest |
| CAS Number | 65928-58-7 |
| Molecular Formula | C??H??NO? |
| Molecular Weight | 311.42 g/mol |
| Dosage Form | Oral tablet |
| Strength | 2mg per tablet |
| Pack Size | 14 tablets × 2 blister packs per box (Total: 28 tablets) |
| Approval Number | H20249426 (China NMPA) |
| Product Code | 86983319000025 |
| Manufacturer | Wuhan Jiulong Renfu Pharmaceutical Co., Ltd. (Changyining Brand) |
| Barcode | 6972217290694 |
| Storage Conditions | Store in a cool, dry place below 25°C; protect from light and moisture |
| Intended Use | Laboratory research only |
Dienogest Tablets Mechanism of Action
Dienogest is a synthetic progestin with selective progestogenic activity. It acts primarily by:
Inhibiting gonadotropin secretion (FSH/LH)
Reducing estrogen stimulation in target tissues
Suppressing ovulation in experimental models
Commonly studied in endometriosis, estrogen-sensitive conditions, and contraceptive research.
Research Applications & Pharmacological Insights
Endometriosis Modeling: Evaluation of anti-estrogenic and anti-inflammatory effects
Hormonal Modulation Studies: Impact on the hypothalamic-pituitary-ovarian axis
Reproductive Endocrinology: Role in ovulation suppression and uterine remodeling
Cancer Research: Dienogest’s impact on hormone-sensitive tumor cells
Combination Drug Studies: Interaction with estrogen or GnRH analogs in lab models
Pharmacokinetics (For Research Purposes):
Absorption: Rapid and complete after oral administration
Half-life: ~9–10 hours
Metabolism: Hepatic (CYP3A4 pathway)
Excretion: Renal and fecal
Safety Profile & Handling
Safety Notes:
In vivo high-dose exposure may affect hormonal balance or liver enzymes
Use appropriate PPE when handling
Avoid exposure by inhalation or skin contact during preparation
Handling Recommendations:
Conduct procedures in a well-ventilated area or fume hood
Dispose of any waste in accordance with lab chemical safety regulations
Avoid contamination of other compounds during analytical or biological assays
?? Research Use Disclaimer
This product is intended exclusively for laboratory research. It is not to be used for therapeutic, diagnostic, clinical, or veterinary purposes. Improper handling may pose safety risks and invalidate experimental data.


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