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Human Interferon ?2b Vaginal Suppository 500,000 IU × 4 (Shuang Yin Jie / Changchun Institute)
$1.00
Human Interferon ?2b Vaginal Suppository (Shuang Yin Jie) is a 500,000 IU recombinant interferon product for gynecological research. Each box contains 4 suppositories. Manufactured by Changchun Institute of Biological Products under NMPA approval S20100006.
?? For laboratory research use only. Not for clinical or diagnostic use.
Description
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Human Interferon ?2b Vaginal Suppository |
| Brand / Chinese Name | Shuang Yin Jie |
| Formulation | Vaginal suppository |
| Strength | 500,000 IU per suppository |
| Pack Size | 4 suppositories per box |
| Dosage Form | Suppository |
| Approval Number | S20100006 (NMPA, China) |
| Product Code | 86903320001491 |
| Manufacturer | Changchun Institute of Biological Products Co., Ltd. |
| Barcode | Not recorded — please contact online pharmacist for assignment |
| CAS Number | Not specified — varies depending on recombinant source |
| Storage | Store at 2–8?°C; avoid freezing |
| Intended Use | For laboratory research use only |
Mechanism of Action
Recombinant Human Interferon ?2b enhances local immune response by activating interferon receptors on epithelial cells, leading to upregulation of antiviral proteins and inhibition of viral replication. It also modulates cytokine production, contributing to localized anti-inflammatory and immunostimulatory effects.
Research Applications & Pharmacology
? Research Applications:
Experimental models of HPV-related cervical erosion
Vaginal mucosal immunity studies
Cytokine response profiling in epithelial tissues
Anti-inflammatory effects in viral cervicitis
Adjunct studies with LEEP or antiviral agents
? Pharmacokinetics & Immunodynamics:
Onset: Local immune activation within 6–12 hours
Bioavailability: Local only; minimal systemic absorption
Activity: IFN-?2b activates STAT1/STAT2 pathway in target cells
Metabolism: Enzymatic degradation at the application site
Half-life: Short; requires consistent application over 7–10 days
Safety Profile & Side Effects
? Observed Reactions in Research Models:
Mild transient vaginal irritation or itching
Local mucosal dryness
Rare low-grade fever (resolves without treatment)
No systemic toxicity at research doses reported
? Handling Notes:
Wear lab coat, gloves, and protective mask
Do not ingest or apply to humans or animals
Store in a refrigerator at 2–8?°C; avoid direct sunlight
Dispose per institutional biosafety protocol
?? Research-Use Disclaimer
This product is intended solely for laboratory research use. It is not authorized for therapeutic, clinical, diagnostic, or veterinary purposes. Improper handling or use in humans may cause harm and violate regulatory guidelines.
Additional information
| Weight | 1.1 kg |
|---|---|
| Dimensions | 18 × 16 × 18 cm |
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