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Tolvaptan Tablets 15mg – For Laboratory Research Use Only
$1.00
Tolvaptan Tablets (Guiyao) provide 15mg of tolvaptan per tablet, with 10 tablets per box. Approved under NMPA H20223417. For research purposes only. Wholesale & retail supported.
?For wholesale prices, other specifications and uses, please consult our staff?
Description
Tolvaptan is a selective vasopressin V2-receptor antagonist used in scientific research related to autosomal dominant polycystic kidney disease (ADPKD) and hyponatremia. It promotes aquaresis without significant sodium loss, making it valuable for studying water-electrolyte balance and renal function.
This research-grade product contains 15mg of tolvaptan per tablet, supplied as 10 tablets per box, and is manufactured by Sichuan Hongming Bosi Pharmaceutical Co., Ltd. under NMPA approval number H20223417.
Note: For laboratory research use only. Not for clinical or diagnostic use.
Product Specifications
| Parameter | Details |
|---|---|
| Product Name | Tolvaptan Tablets (Guiyao) |
| Active Ingredient | Tolvaptan |
| CAS Number | 150683-30-0 |
| Molecular Formula | C26H25ClN2O3 |
| Molecular Weight | 448.94 g/mol |
| Dosage Form | Tablet |
| Strength | 15mg per tablet |
| Quantity | 10 tablets per box |
| Approval Number | H20223417 (China NMPA) |
| Product Code | 86906725000267 |
| Manufacturer | Sichuan Hongming Bosi Pharmaceutical Co., Ltd. |
| Barcode | 6920108100058 |
| Intended Use | Laboratory research only |
| Storage Conditions | Store in a cool, dry place below 25°C |
Mechanism of Action & Research Applications
Tolvaptan is a vasopressin V2-receptor antagonist that inhibits the action of vasopressin in the kidney’s collecting ducts, reducing water reabsorption. This mechanism makes it a valuable tool for:
Research on autosomal dominant polycystic kidney disease (ADPKD)
Hyponatremia and water-electrolyte regulation
Renal function and fluid balance studies
Studies on vasopressin signaling pathways
Potential Side Effects in Animal or In Vitro Studies
Polyuria
Increased thirst
Liver enzyme elevation
Dry mouth
Headache
Handling & Safety
Use Restriction: For research use only.
Protective Equipment: Gloves, lab coat, and eye protection recommended.
Storage: Store below 25°C in a dry, light-protected environment.
Disposal: Dispose of according to institutional chemical waste protocols.
Research Use Disclaimer
This product is intended for laboratory research use only. It is not approved for human, veterinary, diagnostic, or therapeutic applications. Handle in compliance with institutional safety protocols.
Additional information
| Weight | 1 kg |
|---|---|
| Dimensions | 36 × 32 × 36 cm |
Q1: Is this product intended for human use?
A1: No. It is not for human or veterinary use. Research use only.
Q2: Can I order in bulk?
A2: Yes. Both wholesale and retail orders are supported. Contact us for volume pricing.
Q3: Do you provide a COA and SDS?
A3: Yes. A Certificate of Analysis and Safety Data Sheet are available upon request.
Q4: What is the approved indication for the clinical version?
A4: Clinically, tolvaptan is used for ADPKD and hyponatremia under medical supervision.
Q5: What are typical use cases in research?
A5: It is widely used in studies involving kidney function, fluid homeostasis, and vasopressin modulation.
Q6: Is this the same product as Samsca?
A6: It contains the same active compound, tolvaptan, but this product is strictly research-grade.
Q7: How is it typically administered in research?
A7: Orally, via tablet dissolution, or incorporated into animal model feed protocols.
Q8: What is the regulatory approval number?
A8: It is approved under NMPA number H20223417 in China.
Q9: Does tolvaptan affect electrolyte levels in models?
A9: Yes, it promotes water loss without sodium loss (aquaresis), affecting serum sodium concentration.
Q10: Can it be stored at room temperature?
A10: Yes, but store in a cool, dry place below 25°C, away from moisture and light.
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